Transrectal prostate biopsy and fiducial marker placement in a standard 1 5T magnetic resonance imaging scanner

TitleTransrectal prostate biopsy and fiducial marker placement in a standard 1 5T magnetic resonance imaging scanner
Publication TypeJournal Article
Year of Publication2006
AuthorsSusil, R., Menard C., Krieger A., Coleman J., Camphausen K., Choyke P., Fichtinger G., Whitcomb L. L., Coleman N., & Atalar E.
JournalThe Journal of Urology
Date PublishedJan
KeywordsBiopsy, Equipment Design, Feasibility Studies, Humans, instrumentation, instrumentation/methods, Magnetic Resonance Imaging, Male, Needle, pathology, Prostate, Prostatic Neoplasms

PURPOSE: We investigated the accuracy, feasibility of a system that provides transrectal needle access to the prostate concurrent with 1 5 Tesla MRI which previously has not been possible MATERIALS AND METHODS: In 5 patients with previously diagnosed prostate cancer, MRI guided intraprostatic placement of gold fiducial markers (4 procedures),/or prostate biopsy (3 procedures) was performed using local anesthesia RESULTS: Mean procedure duration was 76 minutes, all patients tolerated the intervention well Procedure related adverse events included self-limited hematuria, hematochezia following 3 of 8 procedures (all resolved in less than 1 week) Mean needle placement accuracy was 1 9 mm for the fiducial marker placement studies, 1 8 mm for the biopsy procedures Mean fiducial marker placement accuracy was 4 8 mm, the mean fiducial marker placement accuracy transverse to the needle direction was 2 6 mm All patients who underwent the procedure were able to complete their course of radiotherapy without delay or complication CONCLUSIONS: While studies of clinical usefulness are warranted, transrectal 1 5 T MRI guided prostate biopsy, fiducial marker placement is feasible using this system, providing new opportunities for image guided diagnostic, therapeutic prostate interventions

URLhttp://dx doi org/10 1016/S0022-5347(05)00065-0
PerkWeb Citation KeySusil2006